Introduction: The effect of esophageal distension (ED) on gastric motility has been well documented, but a few investigations have been carried out on the effect of ED on gastric secretion. The aim of this study was to investigate the effect of ED on gastric acid and pepsin secretion and the mechanism(s) involved. Methods: Male adult Wistar rats (200-240 g) were anesthetized with urethane (1...

introduction: recently, hydrogen sulfide has been introduced as the third gas that acts as a transmitter. it has many physiological and pharmacological roles in the human body. the aim of the present study was to investigate the effect of exogenously administered and endogenously produced h2s on the basal and distention-induced gastric acid secretion in rats. methods: forty-nine male wistar rat...

it has been shown that enhanced acid secretion can be suppressed in the rat by systemic administration of glucose. we have recently reported that enhancement of acid secretion as a result of pentagastrin was diminished by intragastric administration of d-glucose. present study was designed to investigate whether intragastric d-glucose influences gastric acid secretion associated with carbachol ...

background many studies have shown that h2s protects the gastric mucosa on different models of stress but till now there are few studies about the effects of h2s on gastric acid secretion. therefore, the aim of the present study was to investigate the role of autonomic nervous system in mediating the inhibitory effect of hydrogen sulfide donor (nahs) on stimulated gastric acid secretion in rats...

Objective: Gut–brain axis (GBA) is very important in creation and modulation of gastrointestinal problems. Aloe vera gel has gastroprotective properties. The purpose of this study was to evaluate the effect of aqueous extract of Aloe vera leaves on the gastric acid secretion and brain and intestinal water content following acetic acid gastric ulcer induction. Materials and Methods: Gastric ulce...

It is well established that the esophageal distention (ED) leads to gastric relaxation, partly by vago-vagal reflex, but till now, the effect of ED on gastric acid secretion has not been investigated. The aim of this study was to investigate the effect of ED on basal and stimulated gastric acid secretion. Methods: Adult male Wistar rats (200-240 g) were deprived of food but not the water 24 h b...

introduction: the effect of esophageal distension (ed) on gastric motility has been well documented, but a few investigations have been carried out on the effect of ed on gastric secretion. the aim of this study was to investigate the effect of ed on gastric acid and pepsin secretion and the mechanism(s) involved. methods: male adult wistar rats (200-240 g) were anesthetized with urethane (1.2 ...

objective: gut–brain axis (gba) is very important in creation and modulation of gastrointestinal problems. aloe vera gel has gastroprotective properties. the purpose of this study was to evaluate the effect of aqueous extract of aloe vera leaves on the gastric acid secretion and brain and intestinal water content following acetic acid gastric ulcer induction. materials and methods: gastric ulce...

sub chronic exposure to lead in rats slows gastric emptying, but little is known about the effects of lead on gastric secretion. this study was designed to investigate the effects of lead on gastric acid secretion and its possible mechanisms in rats. lead acetate was dissolved in drinking water in a concentration of 1%. sodium acetate-containing water with a molar concentration similar to lead ...